(2020-09-12). [Correspondence] Progression-free survival in the ICON8 trial. thelancet.com We greatly appreciate Andrew R Clamp and colleagues'1 report of results from the ICON8 trial, in which they compared two dose-dense weekly chemotherapy regimens with a standard 3-weekly regimen for patients with epithelial ovarian cancer. Instead of summarising the group difference using hazard ratios, Clamp and colleagues summarise the progression-free survival results using clinically interpretable mean and median survival times for each group.2,3…
(2020-09-12). [Clinical Picture] Foot ulcers in systemic sclerosis escape surgical amputation. thelancet.com A 72-year-old woman attended our emergency department with painful ulcers on her left foot (figure). She had a history of Raynaud's phenomenon with two previous ulcers on her feet. She had hypertension—treated with nifedipine—and was taking rivaroxaban for atrial fibrillation. She had no other symptoms. She was a non-smoker and she did not have diabetes. She was having the ulcers dressed three times a week at a local hospital and was being given intravenous iloprost 5 days every month. She was awaiting surgery to have the distal part of her leg amputated because of the severity of the ischaemic lesion…
(2020-09-12). [Perspectives] An activist history of drug shortages and its silos. thelancet.com Her pale green eyes expressed utter fear, but she was adamant that her chemotherapy must stop. At 50 years old, Heather was a widow with two daughters and metastatic breast cancer. The prochlorperazine controlling her nausea, was unavailable, and nothing else seemed to work for her. Doubting that such an old drug could be unavailable, I rang her pharmacist, demanding an explanation. "That's right, doctor", the harried man replied. "There's none in our city, but you can prescribe…", and he listed other, pricier drugs, all ineffective for Heather.
(2020-09-12). Majority of Oregonians believe Portland protests were 'mostly violent' riots, did more harm than good – poll. rt.com 
Around two-thirds of Oregonians disapprove of the protests that have gripped the state's biggest city for over 100 days, while the majority see them as 'mostly violent' and police response as too lax, a poll has found. | Conducted by the non-partisan, Portland-based DHM Research firm this week, the
(2020-09-12). Tulsi Gabbard joins #CancelNetflix campaign, calls 'Cuties' child porn as GOP lawmakers ask DOJ to charge streaming service. rt.com 
Democratic Rep. Tulsi Gabbard has joined calls to "cancel" Netflix over its new film 'Cuties,' dubbing it "child porn" for its sexualized depictions of young girls after two GOP lawmakers urged the DOJ to sue the platform. | The former Democratic presidential hopeful took aim at Netflix in a Friday tweet, arguing the controversial film would only "whet the appetite for pedophiles" and "help fuel the child sex trafficking trade" while slamming the streaming service as "complicit." | .
(2020-09-12). Delayed reaction? Trump's media foe The Atlantic calls to 'end' Nobel Peace Prize after his nomination, but not after Obama's. rt.com 
The two nominations for President Donald Trump for the Nobel Peace Prize — for brokering deals in the Middle East and the Balkans — has prompted The Atlantic to call for the award to be axed, sparking pushback from conservatives. | "End the Nobel Peace Prize," The Atlantic
(2020-09-12). [Department of Error] Department of Error. thelancet.com Kuderer NM, Choueiri TK, Shah DP, et al. Clinical impact of COVID-19 on patients with cancer (CCC19): a cohort study. Lancet 2020; 395: 1907—18—In table 1 of this Article, the indentations for the categories under "Type of malignancy" and "Type of anticancer therapy" were incorrect. These corrections have been made to the online version as of Sept 10, 2020.