(2023-04-22). [Editorial] Routine immunisations: reversing the decline. thelancet.com Over the past 3 years, the COVID-19 pandemic has shown the power and potential of vaccination in real time. But it has also disrupted health services and caused supply chain challenges, resulting in stagnation and backsliding of routine vaccinations. For example, global coverage of the third dose of the diphtheria—tetanus—pertussis vaccine fell from 86% in 2019 to 81% in 2021—the lowest level since 2008. Many other routine vaccinations showed similar reductions. 25 million children missed out on life-saving measles, diphtheria, and tetanus vaccines in 2021.
(2023-04-22). [Comment] State-to-state differences in US COVID-19 outcomes: searching for explanations. thelancet.com In the USA, there has been substantial variation in COVID-19 outcomes across states. In The Lancet, Thomas J Bollyky and colleagues1 explore the reasons for this variation. The authors used correlations and multiple regression to assess the independent contributions of socioeconomic status, income inequality, race, behavioural responses, policy mandates, and support for political candidates to SARS-CoV-2 infection rates, COVID-19 deaths, and educational and employment outcomes. Their analysis showed that wide variations in prepandemic population characteristics between states were strongly associated with COVID-1…
(2023-04-22). [Comment] Even more benefit with endovascular treatment for patients with acute ischaemic stroke: MR CLEAN-LATE. thelancet.com Since 2015 endovascular treatment has been an established treatment for intracranial large artery occlusion up to 6 h after symptom onset or when the patient was last known well.1 The effect of endovascular treatment within 6 h is strong; however, the timepoint when recanalisation therapy becomes ineffective varies between individuals, and some patients might benefit after 6 h. The DEFUSE-3 and DAWN trials tested endovascular treatment up to 16 h or 24 h after symptom onset in patients selected using clinical criteria and perfusion imaging (to identify ischaemic core and tissue-at-risk volumes within strict limit…
(2023-04-22). [Comment] Offline: The UK COVID-19 Inquiry—be patient, but don't wait. thelancet.com Finally, and late, I submitted my witness statement to the UK COVID-19 Inquiry. My reflections are no more or less valid than anyone else's. But this statement was not a voluntary matter. In January, I received a letter asking me to submit my views on the UK's planning, preparedness, and resilience for pandemics between June 11, 2009, and Jan 21, 2020. I did not think this period was within my area of direct experience. The first paper The Lancet published on COVID-19 was on Jan 24, 2020. There are certainly issues I would like to raise about the pandemic after that date.
(2023-04-22). [World Report] Drug developers caution against US mifepristone ban. thelancet.com A lawsuit against the FDA embroils pharmaceutical companies in debates over access to abortion. Susan Jaffe reports from Washington, DC.
(2023-04-22). [World Report] Uganda's "anti-homosexuality" bill already affecting care. thelancet.com Activists and health-care providers are already seeing the chilling effects of Uganda's proposals to further criminalise homosexuality. Sara Jerving reports.
(2023-04-22). [Perspectives] Artesunate versus quinine: the controlled trials watershed. thelancet.com Earlier this century, two inter-related randomised controlled trials—the first in southeast Asia and a second in Africa—provided an incontrovertible breakthrough in the treatment of severe falciparum malaria. The trials, of artesunate versus quinine, proved beyond doubt for the first time that quinine, which had long been the mainstay of treatment for severe malaria, was no longer the most effective drug available, and thus catalysed a watershed in clinical practice and policy making. Like almost all decisive moments, this advance had a backstory that stretched several decades.
(2023-04-22). [Perspectives] Visual representation, medicine, and imperialism. thelancet.com In 1945, just as World War 2 had ended, anti-fascist Bengali writer Premendra Mitra published the first short story of what was to become his science fiction series, Ghana da. Set in 1939, the story, titled Mosha, literally mosquito in Bengali, narrates how the protagonist Ghanashyam Das, alias Ghana da, saved humanity from the scourge of a lethal mosquito designed by a Japanese entomologist named Nishimara, who altered the salivary glands of the mosquito, rendering it more poisonous than a snake.
(2023-04-22). [Obituary] Barbara C Staggers. thelancet.com Paediatrician who championed adolescent health. Born on March 6, 1954, in New York, NY, USA, she died in Castro Valley, CA, USA, on Feb 19, 2023, aged 68 years.
(2023-04-22). [Correspondence] Fluid retention and heart failure in the PRECISION trial. thelancet.com We congratulate Markus P Schlaich and colleagues on the PRECISION trial showing that aprocitentan, an endothelin receptor antagonist, lowered blood pressure more than placebo in patients with resistant hypertension.1 However, we urge caution in accepting the authors' conclusion that aprocitentan was well tolerated.
(2023-04-22). [Correspondence] Fluid retention and heart failure in the PRECISION trial — Authors' reply. thelancet.com We thank Donald E Kohan and Hiddo J L Heerspink for their interest in the PRECISION study and their comments regarding the potential for fluid retention and heart failure associated with endothelin receptor antagonists. Indeed, as described in publications from the past few years,1,2 there was a dose-dependent effect of aprocitentan on oedema and fluid retention occurring in 9 ∑1% and 18 ∑4% of patients treated with 12 ∑5 mg or 25 mg of aprocitentan per day, respectively (2 ∑1% on placebo). As expected, this was accompanied by reduced haemoglobin concentration and increased plasma volume.
(2023-04-22). [Correspondence] Key questions regarding the SYMPLICITY HTN-3 trial. thelancet.com In their Article, Deepak L Bhatt and colleagues1 report results from the SYMPLICITY HTN-3 (Renal Denervation in Patients With Uncontrolled Hypertension) trial, showing that blood pressure in patients with resistant hypertension undergoing renal denervation was lower at 36 months than in patients in the initial sham control group, with adjusted treatment differences of —22 ∑1 mm Hg for office systolic blood pressure and —16 ∑5 mm Hg for 24-h ambulatory systolic blood pressure. These findings are in contrast to those observed at 6 months, when differences in blood pressure between the two groups…
(2023-04-22). [Correspondence] Key questions regarding the SYMPLICITY HTN-3 trial — Authors' reply. thelancet.com In response to our Article,1 Sverre E Kjeldsen and colleagues raise several points that require clarification. The subgroup of patients in the sham control group who did not cross over either did not meet minimal blood pressure requirements or elected not to cross over. These patients had a subsequent rise in systolic blood pressure after unblinding, as shown in the appendix of our Article (p 14).1 Although poor long-term medication adherence remains a plausible explanation for poorly controlled blood pressure in this group, medical inertia is less likely to have occurred in our study because patients had already…
(2023-04-22). [Correspondence] Improving access to global cancer services. thelancet.com A recent Editorial1 highlights the complexity of cancer care, which is burdened by restricted access to expensive and specialist treatment. In many low-income and middle-income countries (LMICs), typical patient journeys are complicated, delaying access to diagnostics for 2—3 months, and serve as a prominent bottleneck to timely treatment.2 Health-care networks in LMICs are not equipped to handle complexity of care; as such, it is crucial to highlight experiences of high-quality models in LMICs as opposed to extrapolating solutions from high-income countries.
(2023-04-22). [Correspondence] Decentralised elements in clinical trials: recommendations from the European Medicines Regulatory Network. thelancet.com Clinical trials of investigational medicinal products (IMPs) increasingly use procedures conducted outside the traditional clinical trial site—a concept referred to as decentralisation. The COVID-19 pandemic highlighted the importance and usefulness of decentralisation when visits to hospitals and other health institutions were restricted. In addition, interested parties, such as from the pharmaceutical industry, issued general plans to introduce more decentralised elements in clinical trials (eg, the Association of Clinical Research Organizations' decentralised trials toolkit1 and Trials at Home).
(2023-04-22). [Correspondence] Rare diseases: democratising genetic testing in LMICs. thelancet.com Although infections are the leading cause of morbidity and mortality, rare diseases are an unexplored burden in low-income and middle-income countries (LMICs). Despite the similar prevalence of autosomal dominant and X-linked conditions in LMICs and in high-income countries, the prevalence of recessive monogenic disorders is higher in LMICs because, in these countries, consanguineous marriages in minority ethnic groups are more frequent.1…
(2023-04-22). [Correspondence] Lessons learned from COVID-19 to stop future pandemics. thelancet.com The pharmaceutical industry delivered billions of safe and effective COVID-19 vaccines at speed but, as highlighted by Els Torreele and colleagues,1 these vaccines did not reach lower-income countries quickly enough. Science delivered, but the equity challenge did not. To acknowledge this, we supported calls for greater sharing of vaccines.2…
(2023-04-22). [Department of Error] Department of Error. thelancet.com Komamura K. Japanese medical workers' sacrifice for universal health coverage. Lancet 2023; 401: 1073—In this Correspondence the second sentence of the second paragraph should read "after April 1, 2024, it will be illegal for clinicians to work more than 960 h of overtime per year (and no more than 100 h of overtime per month)". This correction has been made to the online version as of April 20, 2023.
(2023-04-21). Detienen a 100 personas en operativo de seguridad en Costa Rica. telesurtv.net El Ministerio de Seguridad Pública de Costa Rica indicó que 87 de los arrestados son sospechosos de cometer algún tipo de delito.
(2023-04-21). Acnur alerta sobre situación migratoria en la frontera peruana. telesurtv.net La Acnur y la OIM denunciaron que se han registrado casos de abusos sexuales, aumentando el riesgo de las niñas, mujeres y comunidad LGTBI+.
(2023-04-21). Eclipse total solar oscurece el noreste de Australia. telesurtv.net Partes de Australia, Indonesia y Timor Oriental se vieron inmersos en la oscuridad en pleno día por el eclipse total.
(2023-04-21). Registran 12.591 nuevos casos de Covid-19 en India. telesurtv.net La cartera sanitaria informó que el total de enfermos activos ascendió a 65.286 casos.
(2023-04-21). Inicia edición 45 del Festival Internacional de Cine de Moscú. telesurtv.net Se exhibirán estrenos de autores rusos y películas extranjeras que ya han sido premiadas en certámenes internacionales.
(2023-04-21). Ratifican rechazo a la reforma de pensiones en Ganges, Francia. telesurtv.net Cientos de personas se manifestaron contra la reforma de las pensiones en la pequeña localidad francesa del sur…
(2023-04-21). Continúan protestas contra la reforma judicial en Israel. telesurtv.net La ley pretende otorgar la facultad al Gobierno de seleccionar los jueces que integrarán la Corte Suprema.
(2023-04-21). Reportan dos casos importados de malaria en Cartago, Costa Rica. telesurtv.net Se trata de dos pacientes femeninas, a quienes se les realiza seguimiento.
(2023-04-21). OPS insta a intensificar campañas de vacunación en la región. telesurtv.net La OPS alertó que los programas nacionales de inmunización sufrieron graves retrocesos en la última década.
(2023-04-21). Venezuela y Bolivia firman acuerdos de cooperación. telesurtv.net Los 13 convenios rubricados tienen como propósito reforzar las relaciones bilaterales y profundizar en el proceso de integración.
(2023-04-21). Explosión de minas deja tres muertos en Cundinamarca, Colombia. telesurtv.net Según los últimos reportes, cuatro de los 11 mineros que se encontraban trabajando en la mina de carbón en el municipio colombiano de Cucunubá salieron con vida.
(2023-04-21). Argentina llama a licitación para dragado del Canal Magdalena. telesurtv.net La obra brindará al sur de la provincia de Buenos Aires la posibilidad de exportar con salida directa a aguas profundas.
(2023-04-21). Presidente panameño apoya posible asamblea constituyente. telesurtv.net El mandatario subrayó que se requiere un análisis "fino" para evitar mezclar dicha acción con el proceso electoral.
(2023-04-21). Rechazan en Puerto Rico propuesta de controlar hidroeléctricas. telesurtv.net La autoridad para las Alianzas Público-Privadas requirió a Genera PR presentar una versión del presupuesto.
(2023-04-21). Luis Arce llega a Caracas para fortalecer cooperación. telesurtv.net "Llegamos a la tierra del gran libertador Bolívar, Venezuela, para consolidar importantes acuerdos", señaló Arce.
(2023-04-21). TV BRICS y teleSUR firman acuerdo de cooperación. telesurtv.net La presidenta de teleSUR afirmó que "la alianza entre teleSUR y TV BRICS es un paso hacia el mundo multipolar por el cual luchamos".
(2023-04-21). El presidente cubano recibe al canciller ruso en La Habana. telesurtv.net El canciller ruso manifestó también a su par cubano su satisfacción con la forma en la que se está desarrollando el diálogo político bilateral.
(2023-04-21). Líderes caribeños buscan prohibir armas de asalto para civiles. telesurtv.net Los países miembros de CARICOM hacen un llamado a los Estados Unidos para que se una a la Guerra contra las Armas.
(2023-04-21). Condenan persecución contra Movimiento Sin Tierra en Brasil. telesurtv.net El MST protagoniza este mes varias movilizaciones y actos, con la disposición de abrir un proceso de negociación.
(2023-04-21). Tribunal peruano evalúa prisión contra exministros de Castillo. telesurtv.net El pedido por presunta comisión de los delitos de rebelión y conspiración se examinará desde las 10: 00 (hora local).
(2023-04-21). Extienden uso de ley homófoba en escuelas de Florida, EE.UU. telesurtv.net La extensión amplía la medida a los estudiantes de cuarto y hasta el duodécimo grado, el último nivel del instituto.
(2023-04-21). Renuncia ministro de Seguridad de la Presidencia de Brasil. telesurtv.net El presidente Lula, quien mantenía una antigua amistad con Gonçalves Dias, aceptó inmediatamente la renuncia.
(2023-04-21). Campañas para presidenciales paraguayas entran en recta final. telesurtv.net En los próximos comicios, el ganador de la elección presidencial será el candidato que obtenga el mayor número de votos a través de una única vuelta.
(2023-04-21). Comparecen testigos en juicio político contra Lasso en Ecuador. telesurtv.net La víspera el exgerente de Flopec, Oswaldo Rosero, ratificó que el contrato con Amazonas Tanker beneficiaba a terceros.
(2023-04-21). Gremios franceses prosiguen protestas contra reforma pensional. telesurtv.net El paro afectará a uno de cada cinco trenes regionales en Francia, de acuerdo a las convocatorias de los organizadores.
(2023-04-21). Australia: NSW Labor government closes PCR COVID testing sites. wsws.org The first substantive policy of the new Labor government in Australia's largest state is to prevent working people from getting tested to see if they have a potentially deadly illness.
(2023-04-21). Pentagon leaks intensify political crisis of Zelensky government. wsws.org As all the lies of the imperialist and Ukrainian war propaganda are blown to pieces, the fate of the Zelensky regime is becoming increasingly precarious.
(2023-04-21). US debt ceiling "debate" inaugurates new round of social austerity. wsws.org What has begun in Washington is not a repeat of previous conflicts over budget policy, but a fundamental turn by the US ruling elite to the destruction of long-established benefits like Social Security and Medicare.
(2023-04-21). Sri Lankan president still blocking local council polls while manoeuvring for an early presidential election. wsws.org Wickremesinghe is banking on the enthusiastic support of big business, the media and sections of the upper-middle class over his so-called ability to secure the IMF $2.9 billion bailout loan.
(2023-04-21). Homelessness soars in Australian state of Queensland. wsws.org The number of people accessing homelessness services in Queensland has risen by 22 percent in just four years—the fastest rate nationally.
(2023-04-21). Build a rank-and-file committee to continue the Rutgers strike! wsws.org The IYSSE urges Rutgers academic workers to build an independent rank-and-file committee to take leadership of the struggle out of the hands of the union bureaucracy.
(2023-04-21). "We're replaceable parts to GM, not human": Workers react to accident at Flint Truck plant. wsws.org Workers denounced unsafe conditions at the GM plant after a young worker was nearly crushed by a falling piece of heavy machinery.
(2023-04-21). Following nationwide trend, Iowa Senate passes bill to loosen child labor laws. wsws.org The Iowa bill represents the latest step in the campaign to dismantle child labor protections, amid a surge of child labor violations across the United States.
(2023-04-21). In Germany, Left Party youth group calls for donations to the Ukrainian army. wsws.org Linksjugend (Left Youth) counts among the organisations belonging to the Left Party that aggressively support NATO's proxy war against Russia.
(2023-04-21). Uncrewed SpaceX rocket Starship explodes after launch. wsws.org The company's CEO, Elon Musk, claims the spacecraft will one day ferry humans to Mars.
(2023-04-21). US Supreme Court declines to hear case of Texas prisoner held in solitary confinement for 27 years. wsws.org The nation's high court declined to hear Dennis Hope's appeal of a Court of Appeals decision to dismiss his Eighth Amendment challenge to his imprisonment in solitary confinement for nearly three decades.
(2023-04-20). Gates/WEF-backed Edible Food Coating Already In Use, Cloud-Seeding, Hypocrisy & The CIA. thelastamericanvagabond.com Welcome to The Daily Wrap Up, a concise show dedicated to bringing you the most relevant independent news, as we see it, from the last 24 hours (4/20/23). As always, take the information discussed in the video below and research it for yourself, and come to your own conclusions. Anyone telling you what the truth
(2023-04-20). Workers Struggles: Europe, Middle East & Africa. wsws.org Public sector strike in Greece as workers demand permanent contracts for part-time workers; Stockholm commuter train drivers hold three-day wildcat strike to defend guards, are disowned by union; in Nigeria, aviation workers walked out April 17 over pay and conditions while ExxonMobil workers struck over pay halting oil exports at four terminals…
(2023-04-20). Tens of thousands strike across Norway as Swedish train drivers hold three-day wildcat job action. wsws.org The growth of the class struggle across the Nordic region and its breaking out of the corporatist mechanisms that have suppressed class tensions for decades is inseparable from the transformation of the entire region into a major front in the imperialist powers' war on Russia.
(2023-04-20). South Africa roiled by global crisis of capitalism. wsws.org South Africa, in comparison to its most important trading partners, is a leaf in the gale-force maelstrom of the global economy.
(2023-04-20). Los Angeles teachers union announces sellout three-year deal. wsws.org The agreement was reached to prevent escalating job actions by teachers and school workers and is highly concessionary.
(2023-04-20). Sri Lankan trade unions hold "delegate conference" to derail growing class struggles. wsws.org Union delegates made clear that they will do nothing to stop Wickremesinghe's austerity measures and his anti-democratic attacks.
(2023-04-20). Faculty union ends strike at Illinois universities. wsws.org After isolating striking faculty and staff, University Professionals of Illinois union sent workers back to campuses before they had voted on tentative agreements and without releasing contract details.
(2023-04-20). Australian governments allow Aboriginal communities to be exploited by funeral fund. wsws.org Successive federal and state governments and corporate regulators knew about ACBF-Youpla's exploitive and predatory practices but did little to protect or warn Aboriginal policy holders.
(2023-04-20). Russian pro-NATO oppositionist Vladimir Kara-Murza sentenced to 25 years in prison. wsws.org The charges that were used to imprison Kara-Murza could be used to go after any left-wing critic of the Putin regime's war in Ukraine.
(2023-04-20). Mass layoffs start at Disney as US Federal Reserve's moves to increase unemployment take effect. wsws.org Across the US, job cuts were up 15 percent month-to-month and a whopping 319 percent year-on-year in March.
(2023-04-20). European Central Bank chief warns of global fragmentation. wsws.org Christine Lagarde has warned that there is a danger of the world economy coalescing into two blocs based around the world number one and number two economies.
(2023-04-20). Canada's federal workers' strike and the global resurgence of the class struggle. wsws.org The strike of 120,000 workers is part of a global upsurge of the working class that is driven by the same capitalist crisis propelling the ruling elites in all the major powers towards world war.
(2023-04-20). Fox Corp. to pay $787.5 million for pushing Trump election lies. wsws.org The settlement won by Dominion Voting Systems, falsely accused of helping rig the 2020 elections, was the largest in a US defamation suit.
(2023-04-20). Television and film writers vote overwhelmingly to strike. wsws.org The AMPTP is placing its hopes in the ability of the WGA to control the writers and in its eventual readiness to surrender on the major questions, as it did in the 2007-08 strike.
(2023-04-20). New insight into the possible origin of chipped stone tool technology. wsws.org The use of a hammer-and-anvil technique to crack nuts by monkeys and chimpanzees may represent the precursor of human stone tool technology.
